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Background In esophageal carcinoma, the clinical significance of immunohistochemically (IHC)-detected lymph node (LN) micrometastasis is still controversial. We designed this multicenter study to determine the clinical significance of IHC-detected LN micrometastasis in esophageal carcinoma. Methods The subjects were 164 patients with histopathologically confirmed LN-negative esophageal carcinoma...
The preservation of the recurrent laryngeal nerve is a fundamental skill in cervical procedure such as thyroid, parathyroid or esophagus surgery. Any damage to this nerve could lead to permanent ipsilateral vocal cord paralysis. Therefore this iatrogenic complication must be absolutely avoided by surgeons. However, surgeons rarely encounter the nonrecurrent inferior laryngeal nerve. The aim of this...
The aggressive behavior of esophageal cancer leads to a low survival rate for patients with this disease. Isolated esophageal cancer cells seem to have the potential for regrowth and metastasis. To control the metastasis of esophageal carcinoma, detailed analysis of various molecular and biological factors should be done in each patient. Recent progress in molecular biology has revealed that oncogenes,...
In this study, we reviewed reports on the clinical significance of isolated tumor cells (ITC) in the bone marrow of patients with esophageal cancer and other solid tumor malignancies. We examined studies on bone marrow as a target organ for ITC identification and also looked at the appropriate sites and most efficient methodologies for bone marrow extraction to evaluate the presence of ITC. A diverse...
The patient was a 56-year-old woman. Cervical esophagectomy for cervical esophageal cancer with preservation of the larynx, bilateral neck dissection, and free jejunum reconstruction were performed in our hospital. The oral and anal sides of the free jejunum were reconstructed by end-to-side anastomosis. The oral-side blind pouch of the free jejunum was long, and the jejunum was atonic. We performed...
Background Esophagogastroduodenoscopy (EGD) is frequently requested for patients with gastroesophageal reflux symptoms. When the distal esophagus mucosa shows no erosions, questions are posed: (1) Does the esophageal biopsy contribute to confirm reflux as the cause of the symptoms? (2) Do minimum endoscopic changes have correspondence with histology? Methods A total of 1901 patients were prospectively...
Although intraarterial steroid infusion therapy has previously been shown to be effective for inflammatory bowel disease, it has not yet been applied for the treatment of hemorrhagic radiation gastritis. We report herein a case of hemorrhagic radiation gastritis of gastric tube that occurred after chemoradiation therapy for postoperative peritoneal lymph node metastasis in a patient with esophageal...
Background Thoracoabdominal esophagectomy with three-field lymphadenectomy is considered one of the best treatments for thoracic esophageal carcinoma because the disease is aggressive and lymph node metastasis is common. However, the efficacy of the procedure remains unclear, and it is associated with high postoperative mortality and morbidity. Methods Seventy patients with esophageal carcinoma...
Necrosis of the esophageal conduit is a life-threatening complication in esophageal cancer surgery, and secondary reconstruction options for esophageal discontinuity are quite limited. We present a procedure in which we used a long-segment jejunal flap with a supercharged vascular pedicle to treat gastric tube necrosis following subtotal esophagectomy in a 64-year-old man with esophageal cancer. The...
We report a case of Boerhaave's syndrome developing cardiac tamponade caused by an esophageal leak after primary repair, despite a normal postoperative contrast study. A 65-year-old man underwent emergency surgery for spontaneous esophageal rupture leading to septic shock. He recovered from the septic condition within 2 weeks. Oral intake was started on the 17th postoperative day with no evidence...
Adenocarcinoma of the cervical esophagus arising from the ectopic gastric mucosa is a rare form of tumor, and only 25 cases have been reported previously. We present a case of a 74-year-old man who complained of dysphagia. Esophagogastroduodenoscopy revealed an elevated lesion located on the right posterior wall of the cervical and upper thoracic esophagus. Total esophagectomy and three-field lymph...
We herein report the case of a 50-year-old man with malignant fibrous histiocytoma (MFH) of the esophagus. The patient was admitted to our hospital because of cough, dysphagia, and weight loss. Esophagography and upper gastrointestinal endoscopy revealed a giant protruding lesion in the cervical esophagus. Total esophagectomy was performed with total laryngectomy and pharyngogastrostomy. The tumor...
A 62-year-old man was admitted to our hospital for dysphagia, leukocytosis, and pyrexia. The serum level of granulocyte colony-stimulating factor (G-CSF) was high and immunostaining of a biopsy specimen of esophageal tumor using anti-granulocyte-macrophage colony-stimulating factor (anti-GM-CSF) antibody demonstrated GM-CSF expression in the cytoplasm of the tumor cells. After esophagectomy, the leukocyte...
A 63-year-old man who had a distal subtotal gastrectomy and retrocolic end-to-side gastrojejunostomy was admitted because of a mid-thoracic esophageal cancer. He underwent a two-stage subtotal esophagectomy and reconstruction using the remnant stomach without microvascular anastomosis. We preserved the splenic artery, splenic vein, and the short gastric artery. The remnant stomach was pulled up together...
The indications for endoscopic mucosal resection (EMR) and treatment outcomes are discussed for 402 patients (336 men and 66 women with 527 lesions) who had squamous-cell carcinoma of superficial type and with no lymph-node metastasis (N0) on clinical evaluation. The patients were followed-up for at least 2 years after EMR, conducted between January 1988 and December 2004. They were classified according...
The patient was a 35-year-old man who first underwent fundoplication due to hematemesis associated with reflux esophagitis 11 years earlier. Despite two subsequent antireflux operations, reflux-related symptoms persisted, and upper gastrointestinal endoscopy confirmed recurrent reflux esophagitis. After 24-h pH monitoring and Bilitec 2000 showing regurgitation of gastric and duodenal juice, distal...
An 80-year-old man presented at our hospital with chest oppression and vomiting. An endoscopic examination revealed a tumor in the lower portion of the esophagus, and the patient was diagnosed as possibly having esophageal carcinosarcoma based on a histological examination of endoscopic biopsy specimens. During the initial medical examination, the patient had a high leukocyte count and a high level...
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